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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

QUANTIFICATION OF RIFAXIMIN IN BULK AND PHARMACEUTICAL DOSAGE FORM BY VALIDATED VISIBLE SPECTROPHOTOMETRIC METHODS

Dr. P. G. Sunitha*, E. Senthilkumar, G. Divya, R. Ravikumar, S. Sounthirarajan

ABSTRACT

Two simple sensitive and precise colorimetric methods A and B were developed for the estimation of Rifaximin in bulk drug as well as in pharmaceutical dosage form. Method A is based on the formation of yellow colored chromogen by condensation reaction of Rifaximin with Isoniazid which has absorption maximum at 456nm. Method B is based on the formation of an orange colored complex by oxidation reaction of Rifaximin with 1,10-phenanthroline in the presence of ferric chloride which has absorption maximum at 510nm. The proposed methods are statistically validated and found to be useful for the routine determination of Rifaximin in tablets.

Keywords: Rifaximin, Colorimetry, Tablets, Validation.

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