Abstract

ROLE OF POLYPHARMACY IN THE MANAGEMENT OF MIGRAINE: EXPERIENCE AT A TERTIARY CARE CENTRE

Priyanka Pandey, Nityanand Pandey*, Abhishek Pathak and Dr. Kulwant Singh

ABSTRACT

Introduction: Migraine is a common headache disorder characterized by recurrent attacks. It is the most common type of headache diagnosed in neurological practice and is among the top 10 most disabling disorders worldwide. The aim of the study is to assess the role of pharmacological therapy in the patients diagnosed with migraine. Material and methods: Patients were selected randomly over a period of 30 days. All of them were evaluated, diagnosed and treated by neurospecialists. Patients included in the study were more than 16 years of age with a history of chronic head ache for more than 1 year. Follow up assessment was done based on the documentary evidence in the OPD cards. Result and conclusion: The acute attacks of migraine showed significant relief with non steroidal anti -inflammatory drugs (NSAID) namely naproxen sodium, triptans like sumatriptan and combination of ergotamine and caffeine. Preventive therapy was more complex and included polypharmacotherapy from the antidepressant group, antiepileptic drugs, anti anxiety and sedative drugs.

Keywords: Migraine, pharmacotherapy.