Photo Gallery

Login

Search

News & Updation

  • WJPPS OCTOBER ISSUE PUBLISHED
  • OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

FORMULATION AND EVALUATION OF BIOADHESIVE PULSATILE DRUG DELIVERY SYSTEM OF AN ANTILIPIDEMIC DRUG

Snehal U. Shinde*, Pallavi M. Sangave, Kajal B. Chougule, Sachinkumar V. Patil Shitalkumar S. Patil and Dipak Bhingardeve

ABSTRACT

The main objective of this study is to formulate and evaluate of Bioadhesive pulsatile drug delivery system of an antilipidemic drug. In order to achieve an improved therapeutic efficacy. The present research work describes the combination of Bioadhesive pulsatile principles are very suitable for site and time specific. Gastroretentive drug delivery is an approach to prolong gastric residence time, thereby targeting site specific drug release in the upper gastrointestinal tract (GIT) for local or systemic effects. several gastroretentive drug delivery approaches being designed and developed, including high density (sinking) systems that is retained in the bottom of the stomach, low density (floating) systems that causes buoyancy in gastric fluid, mucoadhesive systems that causes bioadhesion to stomach mucosa, unfoldable, extendible, or swellable systems. The bioadhesive pulsatile tablet was prepared satisfactorily with no weight variation and hardness within official limit. In drug release study lag time up to 7 h. Thus bioadhesivepulsatile drug delivery system is best option for anhyperlipidemic patients.

Keywords: Bioadhesive, gastrointestinal tract, pulsatile, lag time, therapeutic efficacy.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More