Abstract

REVIEW OF ORODISPERSIBLE TABLET USING NOVEL CO-PROCESSING METHOD

Amreen Khan*, Madhavi Kasturi, Sayyed Mohsina, Shuchi Jain and Rupali Partani

ABSTRACT

The purpose of the article is to review potential advancements of ODT technology in drug delivery applications. Now-a-days, orodispersible drug delivery systems are extensively used to improve bioavailability and patient compliance. Over the past three decades, orodispersible tablets (ODTs) have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance, improved solubility and stability profiles. Orally disintegrating tablets (ODTs) are solid dosage forms containing drugs that disintegrate in the oral cavity within less than 1 minute leaving an easy-to-swallow residue. ODTs could be preferred choice especially with those drugs sensitive to GI and for patients under category of pediatrics, geriatrics, bedridden, postoperative and who may have difficulty in swallowing the conventional tablets and capsules. The current article is focused on ideal characteristics, recent trends undertaken to develop ODTs, advantages and disadvantages, various technologies developed for ODT, evaluation methods along with recent research and future potential.

Keywords: Orodispersible tablets, Patented technologies for ODT, Co-processing method Recent research, Improved bioavailability and super disintegrates.