SYNTHESIS AND ANTI BACTERIAL ACTIVITY OF SOME SCHIFF BASES FROM ?-NAPHTHYL AMINE
Shipra Baluja*, Sumitra Chanda And Nirmal Pandya
ABSTRACT
Schiff bases derived from α-naphthyl amine and different aldehydes
were evaluated for their potential as anti bacterial agents against some
gram positive and gram negative bacterial strains such as E. coli, S.
aureus, P. vulgaris, K. pneumoniae and P. aeroginosa in two polar
solvents DMF and DMSO. A differential effect of the compounds in a
particular solvent (DMF / DMSO) inhibited different bacteria to a
different level. This suggests that anti bacterial activity is dependent on
molecular structure of the compound, solvent used and the bacterial
strain under consideration.
Keywords: Synthesis, ?-naphthyl amine, antibacterial activity, inhibition zone.
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