Abstract

EVALUATION OF IN VIVO ANTI-INFLAMMATORY ACTIVITY OF WHOLE PLANT OF Trianthema triquetra ROTTLER EX WILD

K. Sathyaraj* and Dr. R. Indumathy

ABSTRACT

Trianthema triquetra Rottler Ex wild (Aizoaceae) is described in Ayurveda for the treatment of Rheumatism, gout, palsy and amenorrhea. Present study was aimed to investigate the in vivo anti-inflammatory activity of (sirusharanai) whole plant and to support its traditional use. The ethanolic extract of whole plant of Trianthema triquetra (TT) was investigated for its anti-inflammatory activity in carrageenan induced paw edema in Wister albino rats. Two doses of the ethanolic extract (TT 200 and 400mg/kg p.o) were used in the study and Diclofenac sodium (4.5mg/kg i.p) was used as standard. The ethanolic extract of Trianthema triquetra at the concentration of (400mg/kg p.o) significantly (P<0.05) reduced increased in paw volume induced by carrageenan. Trianthema triquetra at the dose of 400mg/kg showed potent anti-inflammatory action on comparison with the standard drug Diclofenac sodium.

Keywords: Trianthema triquetra, Carrageenan, anti-inflammatory, Diclofenac, paw volume.