Abstract

EVALUATION OF IN VITRO ANTI-INFLAMMATORY ACTIVITY OF WHOLE PLANT OF TRIANTHEMA TRIQUETRA ROTTLER EX WILD

K. Sathyaraj* and Dr. R. Indumathy

ABSTRACT

To explore the in vitro anti-inflammatory activity of whole plant of Trianthema triquetra by different in vitro methods. The various extracts (pet. ether, ethyl acetate, ethanol) of Trianthema triquetra whole plant was subjected to in vitro anti-inflammatory activity by RBC membrane stabilization method and protein denaturation (Heat hemolysis) method. An IC50 value was found that ethanolic extract of Trianthema triquetra was more effective in anti-inflammatory activity than that of other extracts. Hence the in vitro studies clearly showed that the ethanolic extract of Trianthema triquetra has a significant anti-inflammatory activity. These in vitro assays indicate that this plant extracts is a better source of natural anti-inflammatory, which might be helpful in preventing the progress of various inflammatory disease.

Keywords: Trianthema triquetra, Aizoaceae, RBC membrane stabilization, protein denaturation, anti-inflammatory.