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  • WJPPS MARCH ISSUE PUBLISHED
  • MARCH 2019 Issue has been successfully launched on 1 March 2019

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  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

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Abstract

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW SERIES OF SCHIFF BASES

Shahare Hitesh Vishwanath *, Mugdiya Yogesh Nemichand, Kharabe Ganesh Parameshwar

ABSTRACT

In the vision of chemistry, Schiff bases play a very important role. The Schiff bases and their complexes have been reported in the literature possessing wide applications in biological, clinical and analytical field. In view of that, in the present work, new substituted Schiff bases were synthesized by a very simple and economical reaction in a good yield. It involves, reaction of 1, 2-diamino benzene with the various substituted aromatic aldehydes in presence of anhydrous ZnCl2, yields corresponding 4, 4’-disubstituteted Bis-(benzyl phenyl) diamine. The synthesized compounds were characterized by their physical constants, TLC, IR and NMR spectroscopy. Further, all the synthesized compounds were successfully evaluated for their antimicrobial activities by cup-plate method.

Keywords: Orthophenylenediamine, Schiff’s base; Imine; Antimicrobial activity.


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