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  • WJPPS APRIL ISSUE PUBLISHED
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Abstract

RESPONSE OF SOME MICROORGANISMS TO THERAPEUTIC (NEWLY EFFERVESCENT CIPROFLOXACIN AND CONVENTIONAL BRANDS)

*Ahmed M. A. Msaad

ABSTRACT

Typhoid is an epidemic disease in Sudan and causes morbidity for many peoples especially in tropical countries.[1] This research aimed to study the response of (Salmonell typhi and Salmonella para typhi) to the ciprofloxacin HCl (effervescent formulae ciprofloxacin and conventional five brands). It is a drug of choice used as an alternative to chloramphincol.[2] Then the microbiological sensitivity test was carried out against (Salmonella typhi, Salmonella para typhi) to detect the response of each one and comparison was held between conventional and unconventional tablets.[3] The results were found that the response of Salmonella typhi is less than Salmonella para typhi, this may be due to genetic factor that found in Salmonella typhi (which make it produce more poly saccharide rather than Salmonella para typhi).[4][19] Interestingly from this research the inhibition zones of effervescent tablets are greater than conventional tablets that may be an indication for more activity and may have quicker using response or action.[5][19]

Keywords: Salmonella typhi, Salmonella para typhi, Effervescent ciprofloxacin HCl, response, Activity.


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