Photo Gallery

Login

Search

News & Updation

  • WJPPS OCTOBER ISSUE PUBLISHED
  • OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

INVITRO ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACT OF ANDROGRAPHIS PANICULATA AGAINST UROPATHOGENS

Murugesan Rajeswari*, Sigamani Ajithadevi, Sengodan Kalaivani and Raja Vinodhini

ABSTRACT

The invitro study was undertaken to identify the antibacterial activity and phytochemical analysis of ethanolic extract of Andrographis paniculata against uropathogens. A total of 100 urine samples were collected from the suspected patients and were examined for the identification of bacteria by standard procedures. Of the 100 urine samples, 47 isolates were identified (gram positive and gram negative bacteria) viz., Escherichia coli 21(44.68%), Klebsiella pneumonia 16(34.04%), Pseudomonas aeruginosa 5(10.63%), Proteus mirabilis 3(6.38%) and Staphylococcus aureus 2(4.25%). The antibacterial activity of crude ethanolic extract of Andrographis paniculata was screened by disc diffusion method. The ethanolic extract shown maximum inhibitory activity against Escherichia coli (21 mm), Klebsiella pneumonia (23 mm), Pseudomonas aeruginosa (19 mm) and Staphylococcus aureus (26 mm) but plant extract was fail to show the inhibitory activity against Proteus mirabilis. The results of antibacterial activity of A. paniculata against selective resistant isolates were compared with the results of standard antibiotics. The study result revealed that the antibacterial properties of A. paniculata might be associated with the presence of phytochemical constituents such as, flavonoids, steroids, terpenoids phenols, tannin, oils and resins.

Keywords: Urine, Andrographis paniculata, Phytoconstituents, Antibacterial activity, Disc diffusion method.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More