EVALUATION OF INVITRO ANTI-INFLAMMATORY, ANTIMICROBIAL AND ANTIOXIDANT EFFECTS OF TRAPA NATANS (LINN.) LEAVES EXTRACT
Deepak Kumar*, Mohammad Rashid and Abhay Pratap Singh
ABSTRACT
Purpose: The purpose of the study is to evaluate invitro antiinflammatory,
antimicrobial and antioxidant activity of leaves of Trapa
natans (Linn.). Methods: Different extracts were prepared i.e., Pet.
ether, Chloroform, Acetone and methanol using soxhlet assembly. All
four extract were tested for the presence of phytoconstituents
(Alkaloid, Carbohydrate, Steroids, Saponin, Phenolic compounds &
tanins, Protein and amino acids) and also evaluate for antiinflammatory,
antimicrobial and antioxidant effects. Results: From
anti-inflammatory activity, It was observed that at a concentration of
2000 μg/ml of methanol extract showed maximum activity 55.61 % as
compared other extracts. From antimicrobial activity, acetone extract
showed maximum activity at a concentraction of 200 mg/ml. The
concentration of 500 μg/ml of methanol extract showed maximum
antioxidant activity 91.75 % in comparision to other extract. Conclusion: Methanol and
acetone extracts were richest in presence of phytoconstituents. From the study methanol and
acetone extracts showed maximum activity as compared to other extracts.
Keywords: Trapa natans, anti-inflammatory, antioxidant, antimicrobial, Erythrocyte, DPPH.
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