WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

FORMULATION AND EVALUATION OF METRONIDAZOLE EMULGELS USING VARIOUS POLYMERS

Anees Fathima*, Amreen Fathima, T.umema Naaz, Shaheen Begum, Nameera Jabeen and R. Soundarya

ABSTRACT

The purpose of the present study was to develop and optimize the emulgel system for Metronidazole using different types of gelling agents: HPMCK4M, Carbopol 940 and Xantham Gum. The prepared emulgels were evaluated in terms of appearance, pH, spread ability, viscosity, drug content and in-vitro drug release. In-vitro release study demonstrated diffusion controlled release of metronidazole from formulation up to 12 hours. The drug release profile exhibited zero order kinetics. All the prepared emulgels showed acceptable physical properties concerning colour, homogeneity, consistency, spreadability, and with higher drug release than conventional gel as per USP. In case of all evaluation parameters carbopol based formulation showed better properties so, As a general conclusion, it was suggested that the Metronidazole emulgel formulation prepared with carbopol highest concentration was the formula of choice.

Keywords: Metronidazole, Carbopol 940, Xanthan Gum, optimization, Anti-Protozoal activity.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More