Photo Gallery

Login

Search

News & Updation

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS DECEMBER ISSUE PUBLISHED
  • DECEMBER 2017 Issue has been successfully launched on 1 December 2017

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.041 to 6.647 due to high quality Publication at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

EVALUATION OF THE ANTIMICROBIAL EFFECTS OF SYZYGIUM AROMTICUM (CLOVE) AND GARCINIA KOLA (BITTER KOLA) EXTRACTS SINGLY AND IN COMBINATION, ON SOME BACTERIA

Ugwu C. C.*, Ezeonu I. M., Mbah-Omeje K., Agu C. G. and Onuorah S. C.

ABSTRACT

Aqueous and organic(or ethanolic and methanolic) extracts of Syzygium aromaticum (clove) and Garcinia kola (bitter kola) were evaluated for their antimicrobial effects against Staphylococcus aureus, Bacillus cereus (NRRL-B-14727) and Pseudomonas aeruginosa using agar well and disc diffusion methods. The ethanolic extract had more inhibitory effect than the aqueous and methanolic extract. The inhibition zone diameters (IZD) for the ethanolic extract of clove ranged between 10 and 35 mm while that of bitter kola ranged between 10 and 20mm. For the aqueous extract, the IZD ranged between 10 and 18 mm for clove and 8 and 18 mm for bitter kola. The IZD for the methanolic extract ranged between 9 and 16mm and 8 and 18mm for Garcinia kola. The combination of these plant extracts produced greater zones of inhibition than the aqueous and methanol extracts used separately. The MIC varied between 3.125 and 6.25 mg/ml as well as 3.125 and 50.0mg/ml for aqueous, ethanolic and methanolic extracts respectively. S. aureus was found to show the greatest sensitivity, while P. aeruginosa showed the least sensitivity of all the isolates. Phytochemical analyses of the extracts revealed the presence of alkaloids, tannins, saponins, flavonoids and essential oils. This study shows that extracts of these plants possess antimicrobial properties which could be used as alternative to conventional antibiotics.

Keywords: Syzygium aromaticum, Garcinia kola, Synergy, Antimicrobial activity, MIC.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More