Abstract

EVALUATION OF INVITRO ANTIOXIDANT ACTIVITY OF VIDANGADI CHURNA

Sajith Mohandas*, Ismail Khalid, Shalin C. and Vandana Ramesh

ABSTRACT

Objective: Vidangadi churna is a traditional polyherbal ayurvedic formulation used in conditions like antifertility, antibacterial, antiprotozoal properties, abdominal disorders, lung diseases and antiinflamatory. It’s composed of Embelia ribes (false black pepper fruit), Hordeum vulgare, Mallotus philippinensis, Terminalia chebula and rock salt. The main aim of the study is to investigate the antioxidant activity of Vidangadi churna. Methods: Aqueous and methanolic extract of the churna were used to investigate antioxidant activity by DPPH radical scavenging assay and reducing power assay. Results: IC50 values of aqueous and methanolic extracts were found to be 63.35 and 147.47 μg/ml respectively by DPPH radical scavenging assay. Aqueous extract of churna showed maximum ferric reducing power to be 0.88 μg/mL. The antioxidant potential may be directly linked to the phenolic compounds present in the ingredients of Vidangadi churna. Conclusion: Vidangadi churna showed significant antioxidant activity.

Keywords: Free radicals, antioxidant, Vidangadi churna, DPPH radical scavenging assay, phenolic compounds.