Abstract

TO STUDY EFFECT OF TOPICAL CLOBETASOL PROPIONATE CREAM ON BLOOD PRESSURE, BLOOD SUGAR AND BLOOD CALCIUM IN HEALTHY VOLUNTEER

Chetan Sushil Javsen* and Dr. Y. A. Deshmukh

ABSTRACT

Corticosteroids are mainly used to reduce inflammation and suppress the immune system. Corticosteroids are used in a variety of conditions, ranging from brain tumours to skin diseases. Short-term corticosteroid use is associated with generally mild side effects, including cutaneous effects, electrolyte abnormalities, hyperglycemia, pancreatitis, hematologic, immunologic and neuropsychologic effects. Long-term corticosteroid use may be associated with more serious sequel, including osteoporosis, hypertension, adrenal insufficiency, gastrointestinal, hepatic and ophthalmologic effects, hyperlipidaemia, growth suppression and possible congenital malformations. Blood pressure, blood sugar and blood calcium level were measured before and four hours after drug application. There is no clinical significant different in blood pressure, blood sugar and blood calcium before and four hours after Clobetasol propionate cream application.

Keywords: Topical, Clobetasol propionate cream, blood pressure, blood sugar, blood calcium.