ANTI-OXIDANTPOTENTIAL OF ACHYRANTHES ASPERAL.:INVITRO APPROACH
TajdarHusain Khan*, MajidAhmed Ganaie, NasirAli Siddiqui, Aftab Alam, MohdNazam Ansari
ABSTRACT
Objective: Reactive oxygen species, such as hydroxyl radical,
hydrogen peroxide, and superoxide anions, are produced as by
products in aerobic organisms, and have been implicated in the
pathology of a vast variety of human diseases. Antioxidant activity is
an important in-view of the free radical theory of many diseases.
Methods: In the present study, acetone, ethyl acetate, n-butanol, and
methanol extracts of Achyranthes asperaL. were evaluated for radical
scavenging activity by studying the inhibition of the level of lipid
peroxidation induced by Fe(++)/ascorbate, DNA sugar damage,
scavenging of hydrogen peroxide, DPPH radical scavenging activity,
total phenolic content, total flavonoids content and total
proanthocyanidin. Results: The maximum free radical scavenging
potential was found with the methanol extraction of A. aspera.
Conclusion: The results suggest that the extracts can be a vital source of phytochemical
antioxidants.
Keywords: Achyranthes asperaL.;DNA sugar damage; DPPH; antioxidant.
[Download Article]
[Download Certifiate]