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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

MICROWAVE ASSISTED SYNTHESIS AND ANTI MICROBIAL ACTIVITY OF SOME NOVEL BENZTHIAZOLO PYRAZOLO QUINOXALINE COMPOUNDS

Tejasri Alla*, Swetha Naram Reddy, Kavya Esarapu, Jainendra Kumar Battineni, Vasudha Bakshi

ABSTRACT

A novel series of Benzthiazolo pyrazolo quinoxaline derivatives 6(a-e) have been synthesized and evaluated for anti-microbial activity by creating a new molecular frame work. Five new compounds were synthesized by treating chalcone 5(a-e), with benzoic acid hydrazide to yield Benzthiazolo pyrazolo quinoxaline compounds 6(a-e), by utilizing microwave energy. The structures of these newly synthesized compounds were confirmed by their spectral data and elemental analysis. These compounds have been screened for their anti-microbial activity. Towards all tested organisms compounds 6c, 6d and 6a give a significant anti bacterial activity, when compared with that of standard drug ampicillin. Also 6c, 6d and 6e compounds show moderate degree of anti fungal activity when compared with fluconazole.

Keywords: anti microbial activity, benzthiazolo pyrazolo quinoxaline erivatives, benzoic acid, fluconazole, chalcone.

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