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Abstract

EVALUATION OF DIURETIC AND NEPHROPROTECTIVE ACTIVITY OF DESMOSTACHYA BIPINNATA IN ALBINO RATS

Azmath Farhana*, Swetha Naram Reddy, Teja Sri. A, Aliya Anjum and Vasudha Bakshi

ABSTRACT

Diuretic activity and nephroprotective activity of different extracts of Desmostachya bipinnata in rat was studied. The study suggested that the extracts have good diuretic property. Diuretic study was carried out as per Lipschitz method. Where successive aquoeus, ethonolic and petroleum extracts were studied for diuretic activity. The 6 hrs acute study of successive aqueous, ethonolic extracts showed increase in urine volume and K+ ion excretion as compared to control. However advanced toxicological studies remain to be performed in rodents. Extracts have shown moderate nephroprotective effect against gentamicin induced nephrotoxicity.

Keywords: Desmostachya bipinnata, nephroprotectective action, lipschitz method.


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