Photo Gallery

Login

Search

News & Updation

  • WJPPS JUNE ISSUE PUBLISHED
  • JUNE 2017 Issue has been successfully launched on 1 June 2017

  • ICV
  • WJPPS Rank with Index Copernicus Value 52.51 due to high reputation at International Level

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.041 to 6.647 due to high quality Publication at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

IN-VITRO AND IN-SILICO SCREENING OF ACETYLCHOLINESTERASE INHIBITOR EXTRACTED FROM EPIPREMNUM AUREUM; A SOLUTION FOR ALZHEIMER’S

Shouvik Pine, Nitisha Bhargava and Guruprasad R*

ABSTRACT

Acetyl cholinesterase enzyme metabolise the transmission of action potential across the neuromuscular and catabolised the hydrolytic destruction of the cationic neurotransmitter acetylcholine. As acetyl cholinesterase (AChE) inhibitors play a fundamental role in therapeutic alleviate in Alzheimer’s disease .The naturally occurring organic compounds from plants are considered to be plenty source of new inhibitors has lead to the discovery of new drugs. In this paper we have isolated the inhibitors from Epipremnum aureum. This compound were documented by using GCMS, and simultaneously docking studies were done. We have analysis the efficacy of plant extract in both in-vitro and in-vivo condition by using zebrafish as a model organism. The plant extract has revealed many inhibitory activities in both in-vitro and in-vivo condition. With further research this compound may be used for the treatment of Alzheimer’s

Keywords: Acetylcholine, acetyl cholinesterase, GCMS.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More