Photo Gallery

Login

Search

News & Updation

  • WJPPS JULY ISSUE PUBLISHED
  • JULY 2017 Issue has been successfully launched on 1 July 2017

  • ICV
  • WJPPS Rank with Index Copernicus Value 52.51 due to high reputation at International Level

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.041 to 6.647 due to high quality Publication at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

IN-VITRO CYTOTOXICITY OF THREE SELECTED MEDICINAL PLANT EXTRACTS FROM KENYA.

*Kimutai Nicholas

ABSTRACT

In Kenya, medicinal plants have been used by the local people as traditional medicine to treat different human ailments from time immemorial. However, safety of most of these plants has not been determined hence the present study seeks to determine the in vitro cytotoxicity of the three medicinal plants namely; Ehretia cymosa Thonn, Dovyalis abyssinica (A. Rich.) Warb. and Periplocca linearifolia Dill & A. Rich that are commonly used to treat various diseases. The ethnobotanical survey was carried out using a structured questionnaire. Fresh plants were collected from the field and air dried under shade at 25oC and later ground into powder and extracted using acetone and water. In vitro cytotoxicity test was carried out following a modified rapid calorimetric assay using actively dividing sub-confluent Vero E6 cells. Cell toxicity showed that most of the plant extracts tested were not cytotoxic having a CC50(μg/ml) of ≥100 against Vero cell lines except the acetone extracts of P. linearifolia that were moderately toxic with a CC50(μg/ml) of 12.5, suggesting former extracts may be safe as antimicrobials.

Keywords: Cytotoxicity, Extracts and Medicinal Plants.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More