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Abstract

IRSA (IRIS ENSATA) AND ITS EFFECT ON SAFETY PARAMETERS: A CLINICAL STUDY ON THE PATIENTS OF ILTEHABE UNQUR REHM (CERVICITIS)

*Salma Mirza

ABSTRACT

Iltehabe Unqur Rehm (cervicitis) refers to the inflammation of the cervix which may be acute or chronic causing various complications. Hence it has been decided to conduct a clinical trial for its management with Irsa. This study was a randomized single blind standard controlled trial. It had been undertaken in the department of Ilmul Qabalat wa Amraze Niswan NIUM, Bangalore. All the patients were randomly allocated to test and control group (30 patients in test group & 15 patients in control group. Duration of study is one and a half year. Irsa was given in the form of majoon, 10 gm in two divided doses after menses for 15 days for three cycles and extract of Irsa (10ml) was prepared and used locally in night in the form of humool (pessary) after menses for 15 days for three cycles. In the control group tablet doxycycline 100mg BD was given orally after menses for 7 days for three cycles. Vaginal pessary of a combination of clindamycin, clotrimazole and metronidazole OD was given locally in night after menses for 7 days for three cycles. The results were analyzed statistically using Chi Square and Paired Student‟t‟ test. Results: Patients treated with the test drug showed a cured and relieved rate of 76.7%, partially cured and relieved rate was 16.7 % and not cured and relieved rate was 6.7% in comparison to control group where cured and relieved rate was 33.3%, partially cured and relieved rate was 26.7% while not cured and relieved rate was 40% which is statistically significant (p<0.01). Student t test (paired) was used to find the homogeneity of parameters. Here P.val > 0.05, it is considered non- significant. Interpretation and Conclusion: The study revealed that the test drug is effective and safe. So, the trial drug can be recommended to manage it.

Keywords: Iltehabe Unqur Rehm; Cervicitis; Unani formulation.


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