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Abstract

SERUM VITAMIN D LEVELS IN PULMONARY TUBERCULOSIS

Saurabh Kumar Deo*, Neeru Bhaskar and Sameer Singhal

ABSTRACT

Vitamins are known to be associated with immunity and nutrition. Moreover, vitamin deficiency can affect host immunity to various infectious diseases, including tuberculosis. We performed a casecontrol study to investigate the serum vitamin D concentrations in 100 patients with pulmonary tuberculosis (PTB) and 100 control subjects and it was found that the mean serum vitamin D levels in pulmonary tuberculosis (PTB) patients were 24.08 ± 14.59 ng/ ml with a range of 5.7 – 98.3 ng/ml and in control subjects the mean serum vitamin D levels were 31.08 ± 11.31 ng/ml with a range of 14.2 – 85.5 ng/ml and the difference between two groups found to be statistically highly significant (p<0.001). The mean serum vitamin D levels in male and female hypovitaminosis D within PTB groups were 18.44 ± 7.31 and 18.93 ± 6.49 ng/ml, respectively. In conclusion, vitamin D deficiency is common in patients with PTB.

Keywords: Vitamin D, pulmonary tuberculosis, immunity, hypovitaminosis.


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