Abstract

EVALUATION OF EFFICACY OF MAJOONE REVAND IN ALCOHOLIC HEPATITIS

Dr. Nadim Ahmad* and **Prof. Mansoor A. Siddiqui

ABSTRACT

Alcoholic hepatitis is a much more severe lesion than alcoholic fatty liver and is often a precursor to the development of cirrhosis. Excessive alcohol consumption is the third leading preventable cause of death in the world. Unani scholars were well acquainted with the basic concept of this disorder. Warm kabid har safravi as described in literatures are supposed to be caused due to excessive alcohol consumption. The symptom and signs of alcoholic hepatitis are abdominal pain, anorexia, low grade fever, nausea, vomiting, enlarged liver, yellow coloured urine, breathlessness etc depending upon the site of involvement. The full picture of a florid, acute alcoholic hepatitis is relatively rare. There are all gradations of severity. The hepatitis may be separate or can be combined with an established cirrhosis. A randomized single blind comparative trial with the three formulations was conducted in 60 cases randomly assigned into three groups; 20 cases of Group A was subjected to the Majoon Revand, 20 cases of Group B was treated with Liv 52 once daily and 20 cases of Group C were treated with plain Glucose solution, followed up for 45 days. The results were analyzed statistically by Friedman test and Wilcoxan matched signed rank test for within group and Kruskal-Wallis test for between the groups with Dunn’s multiple comparison test.

Keywords: Warm kabid har safravi; alcoholic hepatitis; Majoon Revand; Unani.