WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF KETOTIFEN AND SALBUTAMOL IN BULK AND DOSAGE FORM

*Raval Kashyap, U. Srinivasa

ABSTRACT

A simple, accurate and precise High Performance Liquid Chromatographic (HPLC) method has been developed for simultaneous determination of Ketotifen and Salbutamol in bulk and dosage form. The method has been validated as per the guidelines of ICH. The separation is achieved on 250*4.6mm C18, 5micron (Hypersil BDS) column with flow rate 1.0 mL per minute in isocratic mode using Buffer pH 3.5(0.1% triethylamine): Acetonitrile(60:40) as mobile phase. Column oven temperature is maintained at 25°C. The linearity range was found to be in the range of 5-15 μg/ml for Ketotifen and 10-30 μg/ml for Salbutamol. Correlation co-efficient for calibration curve of Ketotifen and Salbutamol was found to be 0.9988 and 0.9989 respectivelyThe method is simple, accurate, reproducible and short and can be used for simultaneous analysis of Ketotifen and Salbutamol.

Keywords: Ketotifen, Salbutamol, Buffer pH 3.5 and Acetonitrile.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More