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  • WJPPS SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2018 Issue has been successfully launched on 1 September 2018

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  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

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Abstract

SYNTHESIS, ANTIMICROBIAL AND ANTI MYCOBACTERIAL ACTIVITY OF SOME CHALCONE DERIVATIVES OF INDANE-1,3- DIONE.

Siddharth Desai* and Dr. V. Girija Sastry

ABSTRACT

In the continuous study of our research program,initially we synthesized some chalcone derivatives of indane-1,3-dione using conventional method by reacting 2- acetyl indane-1,3- dione(1) with different aromatic aldehydes.For this, compd(1) was obtained by reacting phthalic anhydride with acetic anhydride and acetyl acetone in the presence of triethyl amine. The synthesized compounds(2a-f) have been characterized by TLC, IR and.1H-NMR spectroscopy and evaluated for their antibacterial, antifungal and antitubercular activities.

Keywords: Chalcone, indane-1,3-dione, aromatic aldehydes, antitubercular activity.


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