WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

TO STUDY THE EFFECT OF HIBISCUS ROSA FOR THE TREATMENT OF ACUTE AND CHRONIC INFLAMMATION

Sultana Zakiya*, B.B. Panigrahi, Rehana Parveen, Ranjeet Kumar Bhargav, Abhay Kumar Verma and Priyanka Shrivastav

ABSTRACT

Inflammation is a localized reaction that elicited in response to mechanism injuries, burns, microbial infection, allergens and noxious stimulus. The inflammatory response is a highly regulated biological process that enables the immune system to efficiently remove the injurious stimuli and initiate the healing process. It also establishes memory that enables the host to mount a faster and more specific response upon a future encounter which leads ultimately to the restoration of tissue structure and function.[1] The process of inflammation is necessary in healing wounds. However, uncontrolled and persistent inflammation contributes to the progression of many chronic pathological condition such as rheumatoid arthritis. Atherosclerosis, psoriasis, inflammatory bowel disease, retinitis, multiple sclerosis etc. It may also be associated with increased risk of cancer.[2] It is a short term response that usually results in healing process.[3] The acute phase begins with the production of mediators by resident cell in the injured or infected tissue that promote the exudation of proteins and influx of granulocytes from the blood. The leukocyte typically neutrophils, phagocytosis and eliminate foreign microorganism. This process is followed by an event accompanied by active anti-inflammatory and pro-resolution process.[4] In the chronic phase, inflammation is characterized by the development of specific humour and cellular immune response to the pathogens present at the site of tissue injury. It is a prolonged, deregulated and maladaptive response that involves active inflammation, tissue destruction and attempts at tissue repair. This phase involves infiltration of mononuclear immune cells: monocytes, macrophages, lymphocytes, and plasma cells. Inflammatory process involves synthesis and release of local inflammatory mediators such as prostaglandins (PGs), leucotrienes (LTs) and platelet activating facto (PAF) induced by phospholipaseA2 (PLA2), cyclo-oxygenase (COXs) and lipo-oxygenase (LOXs). Besides, other important inflammatory mediators including chemokines, cytokines, vasoactive amines, kinins, nitric oxide (NO) are also released during inflammatory process.[5]

Keywords: Hibiscus Rosa Sinensis Linn, Carrageenan, paw edema, anti-inflammatory.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More