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  • APRIL 2019 Issue has been successfully launched on 1 April 2019

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Neethu Varghese*, Jemi Jacob, Mythri M., Nija B., Sheeba Jasmine T. S.


A number of heterocyclic derivatives containing nitrogen have been used as versatile scaffolds in drug development. Thiazole is one of the heterocyclic compounds with remarkable pharmacological activities. Thiazole derivatives were found to possess the biological activities like anti-convulsant, anti-microbial, anti-inflammatory, anti-cancer, anti-HIV, anti-diabetic, anti-alzheimer, anti-hypertensive, anthelmintic and anti-oxidant activities. Due to its potent and significant biological activities it has great pharmaceutical importance; hence, synthesis of this compound is of considerable interest. This review mainly focuses on the research work reported in the scientific literature on different synthetic procedures of Thiazole compounds.

Keywords: Synthesis, 1,3-thiazoles,Thiazole derivatives, substituted thiazole.

[Full Text Article]

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