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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

SYNTHESIS, ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITY OF SOME NEW 2-PYRAZOLINES

Dr. Ch. Prasad*, Dr. Y. Srinivasa Rao and A. Kanakaraju

ABSTRACT

A new series of chalcones (1a-h) were synthesized by condensation of 3-acetyl-2,5-dimethyl thiphene with various substituted aromatic aldehydes by claisen – Schmidt condensation method. The resulted chalcones react with phenyl hydrazine HCl in presence of pyridine to give 1,3,5 – Trisubstituted 2-Pyrazolines CHP (1-8). All these pyrazolines were characterized by means of their IR, H1NMR and elemental analyses. Newly Synthesized compounds were evaluated for anti-inflammatory, antibacterial and antifungal activities.

Keywords: 2-Pyrazolines, Synthesis, Anti-inflammatory and antimicrobial activity.

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