Abstract

BREAST DIAGNOSTIC IMAGING (US, MRX) VS CORE BIOPSY HISTOLOGY: ANALISYS OF THE CAUSES OF MISMATCH

Khodor Haidar Hassan*, Diego De Benedetto, Giulia Bicchierai, Ermanno Vanzi Cecilia Boeri, Francesco Lucci, Icro Meattini, Jacopo Nori

ABSTRACT

Percutaneous core breast microbiopsy is an increasingly commonly used method for diagnosis of breast pathologies. The correlation between imaging and the histological result, which has always played a fundamental role in surgical biopsy of non-palpable breast lesions, is also of critical importance in image guided percutaneous core biopsies and it is a useful tool for estimating the accuracy of the procedure. The mismatch between the histological results and the diagnosis suggested by the imaging, can indicate that the lesion was not adequately sampled which could lead to failure to diagnose or misdiagnosis of a probable malignant lesion. The aim of this work is to present our experience with percutaneous breast microbiopsy on uncertain orsuspect mammary lesions seen with a mammogram and/or ultrasound. Our analysis of the results of 10,000 cases evaluates the occurrence of mismatches between the probable diagnosis derived by the imaging and the histological result of the biopsy and considers possible causes of these mismatches.

Keywords: Breast cancer, Percutaneous core breast microbiopsy,(MRI), microcalcifications, mammogram, US ultrasound.