Abstract

SENSITIVITY PATTERN OF OPPORTUNISTIC BACTERIAL PATHOGENS OF HIV/AIDS PATIENTS ON CYCLEA PELTATA (LAM.) HOOK.F. & THOMSON - A POTENTIAL MEDICINAL PLANT.

Thangaraj Francis Xavier*, Moorthy Kannan and Anthonysamy Auxilia

ABSTRACT

Objective: To examine the sensitivity pattern of Cyclea peltata (Lam.) Hook. f. & Thomson. (Malaithangi) against opportunistic bacterial pathogens isolated from HIV/AIDS patients of Namakkal district. Methods: The fresh plant root were collected from Kolli Hills of Eastern Ghats, Tamil Nadu. The dry crude petroleum ether, chloroform, ethanol, methanol and acetone extracts of root of Cyclea peltata were used to examine the antibacterial activity using disc diffusion method. Results: All the extracts showed varying degree of inhibitory zones against all the tested bacteria. Ethanol root extract had higher inhibitory zones against Staphylococcus hominis, Staphylococcus aureus, Klebsiella oxytoca, Pseudomonas aeruginosa, Salmonella typhi, Proteus mirabilis and Serratia marcescens. Petroleum ether root extract showed maximum inhibition zone against Staphylococcus hominis and Klebsiella oxytoca. Conclusion: The present investigation showed the effectiveness of crude extracts of this plant against tested opportunistic bacterial pathogens. This study additionally suggested the use of Cyclea peltata root extract in treating diseases caused by tested opportunistic bacterial species.

Keywords: Opportunistic pathogens, Cyclea peltata, Kolli hills, Antibacterial activity, Ethanol extract.