Abstract

A REVIEW ON: LIPOSOMES

Rutuja Ravindra Deshmukh*, Snehal Vijay Gawale, Megha Kailas Bhagwat, Priyanka Arvind Ahire and Nikita Diliprao Derle

ABSTRACT

Different types of pharmaceutical carriers are to deliver drug to particular target cell type. They are – particulate, polymeric, macromolecular. Particulate type carrier also known as colloidal carrier system, includes lipid particles (low and high density lipoprotein-LDL and HDL, respectively), microspheres, nanoparticles, polymeric micelles and the vesicular like liposomes, niosomes pharmacosomes, virosomes, etc.Liposomes — microscopic phospholipid bubbles with a bilayered membrane structure — have received a lot of attention during the past 30 years as pharmaceutical carriers of great potential. Liposomes, which are biodegradable and essentially nontoxic vehicles, can encapsulate both hydrophilic and hy drophobic materials, and are utilized as drug carriers in drug delivery systems. As a result, numerous improvements have been made, thus making this technology p otentially useful for the treatment of certain diseases in the clinics. Many liposome based DNA delivery systems have been described, including molecular components for targeting given cell surface receptors or for escaping from the. This review discusses the potential applications of liposomes in drug delivery,their preparation method, targeting, mechanism of formation, liposome component and the problems associated with further exploitation of this drug delivery system.

Keywords: Liposomes, classification, methods of preparation, applications.