Abstract

NANOPARTICLES AS DRUG DELIVERY SYSTEM IN MODERN TRENDS

Nouratan Singh*, Prof. Dr. Dalel Singh2, Dr. Neeraj Tandan*, and Dr. S. P. Singh

ABSTRACT

Drug’s influence on vital tissues and undesirable side effects can be minimized if drug is transported to the place of action. Compare to the traditional forms of drugs, Drug delivery systems (DDS) have several advantages. Accumulation of therapeutic compounds in the target site, increases and consequently the required doses of drugs are lower. This recently form of therapy is especially important when there is a discrepancy between the dose and the concentration of a drug and its therapeutic results or toxic effects. Cell-specific targeting can be accomplished by attaching drugs to specially designed carriers. Various nanostructures, including such as liposomes, polymers, dendrimers, silicon or carbon materials and magnetic nanoparticles, have been tested as carriers in drug delivery systems, nanocarriers and their connections with drugs are analyzed. Special attention is paid to the functionalization of Carbon nanohorn single-wall (CNHSW) are another type of nanocarbon material that has the potential to be useful in nano-medicine. CNHSW has a horn-tipped, tubular single-walled graphite structure and is between 2 to 5 nm in diameter and between 40 to 50 nm in length, considerable attention due to their unique structure and properties, which make them promising materials for use in biomedical applications are discussed.Drug delivery system, nanocarriers, nanoparticles, liposomes, carbon nanohorn, targeting therapy.

Keywords: Drug delivery system, nanocarriers, nanoparticles, liposomes, carbon nanohorn, targeting therapy.