Abstract

EVALUATION OF ANXIOLYTIC ACTIVITY OF BARK AND ROOT EXTRACTS OF GARCINIA GUMMI GUTA (L.) N.ROBSON

Mathew George, Lincy Joseph and Ashitha K. S.*

ABSTRACT

Objective: To study the effect of ethanolic bark and root extract of Garcinia gummi guta (L.) N.Robson has anxiolytic activity on Swiss albino mice. Methods: Bark and root of Garcinia gummi guta (L.) N.Robson was collected and extracted using ethanol by cold maceration. The crude extracts were screened for the biological activity through the assay of anxiolytic activity. Anxiolytic activity evaluated by using in vivo methods such as plus maze, hole board and Y-maze. Result: Ethanolic bark and root extract Garcinia gummi guta (L.) N.Robson has anxiolytic activity. The result of the study showed that bark extract was more anxiolytic agent than the root extract. Conclusion: The result indicates that Garcinia gummi guta (L.) N.Robson was an anxiolytic agent.

Keywords: Anxiolytic activity, Garcinia gummi guta (L.) N.Robson Swiss albino mice.