Abstract

GC-MS ANALYSIS OF METHANOLIC EXTRACT FROM THE INTERNAL SHELL OF CEPHALOPODS

Jemma Hermelin Jesy Diaz* and R. D. Thilaga

ABSTRACT

The marine environment is a rich source of both biological and chemical diversity. This diversity has been the source of unique chemical compounds with the potential for the development of new pharmaceuticals. The cephalopod bone are a source to be considered in the discovery of new substances for drug development because of their pharmacological properties. The present study was carried out to characterize the bioactive substance present in Loligo duvauceli (squid) and Sepia pharaonis (cuttlefish) internal shell by GC-MS analysis. GC-MS analysis revealed the presence of ten active compounds in the squid. Among the identified compound an amide compound 9-octadecenamide was found to be in the maximum percentage (15.08). Seven compounds were confirmed in the cuttlebone extraction with the maximum percentage of uric acid (15.66%). These compounds might be responsible for their bioactivity. A thorough understanding of chemical structure and biological activity will lead to the formulation of novel drugs with specific activity.

Keywords: Chemical diversity, Pharmacological property, internal shell, GC-MS.