Abstract

VITAMIN D IN SYSTEMIC LUPUS ERYTHEMATOSUS

Jamal Albishri*, Khalid Alsubai, Hemail Alsubai

ABSTRACT

Vitamin D deficiency has been recognized as a very frequent vitamin deficiency worldwide.[1] Giving that the synthesis of vitamin D is initiated in the skin by UVB radiation, persons with lower than normal exposure to sunlight are at higher risk of vitamin D deficiency, which is supported by scientific evidences.[2] Vitamin D sufficiency is defined as blood concentration of 25-hydroxyvitamin D [25(OH)D] of at least 30ng/mL, according to The Centers for Disease Control and Prevention[3] (Table1). Recent reviews have demonstrated that the number of individuals with inadequate blood levels of vitamin D is constantly increasing. Sufficient levels of vitamin D were found in 60% individuals in the period 1988-1994 and in 30% of individuals during the period 2001-2004.[4] Severe vitamin D deficiency is defined as 25(OH)D blood level <10ng/mL and it has increased from 2% to 6% during the same period.

Keywords: .