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Abstract

EFFECT OF HAEMODIALYSIS ON SOME METABOLIC PRODUCTS OF CKD PATIENTS IN LIBYA

Khaled M. D., A. Faiz, A. T. Abdelgader, S. Bioprabhu* and E. I. Elshafie

ABSTRACT

Chronic kidney disease (CKD) represents lose of kidneys normal function over 1/3 for more than three months. Sometimes kidney disease leads to kidney failure, which requires dialysis or a kidney transplant to keep people alive. More often kidney function worsens over a number of years. Objective of this cross sectional study is to assess the level of different metabolic (carbohydrate, Proteins and minerals) end products of CKD of Pre-Haemodialysis and Post Haemodialysis patients at Al-khoms teaching hospital, Al-khoms, Libya. Total of 71 (42 male and 29 female) cases of CKD with Haemodialysis (HD) are included in the study. Blood samples are collected and centrifuged to take serum. Blood sugar, Urea and Uric acid, different Proteins and different minerals are analysed from the serum of CKD patients before and after HD using latest equipments. Blood sugar and Urea concentrations of some patient show alarming level than the normal level. Uric acid level is also in highest level but not exceeded the normal value. Total Protein, Albumin and Creatinine amounts are in dangerous level (above the normal amounts) in most of the patients. But the level of Blood sugar, Urea, Uric acid and Total protein are controlled in Post HD cases. Amount of Albumin in females are more than the male. Blood sugar and albumin levels are increased with an increase of age. Minerals like Ca levels are more in Post HD cases than the Pre-HD cases. Other minerals like K, Na and P levels are decreased by HD. Calcium level in the blood is also increased with an increase of age. Blood sugar, Urea, Uric acid, Total protein, Albumin and Creatinine levels are increased significantly than the normal or show highest level reveals that the patients involved in the study have CKD (p˂0.05). Male cases have more levels of Blood Urea, creatinine and Phosphorus than the female.

Keywords: Haemodyalysis, Metabolic products, CKD, Libya.


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