Abstract

GC-MS ANALYSIS OF BIOACTIVE COMPONENTS FROM ETHANOL EXTRACT OF ANDROGRAPHIS PANICULATA.

V. Sivakumar* and G. Gayathri

ABSTRACT

Medicinal plants are sources of important therapeutic aids for alleviating human ailments. Andrographis paniculata is one of the medicinally important plants belonging to the family Acanthaceae, commonly known as “Nilavembu” in Tamil. The present investigation was carried out to determine the chemical components present in the Andrographis paniculata medicinal plant by GC-MS technique. The major phytocomponents found in 3,7,11,15-tetramethyl-2-hexadecen-1-ol (14.82), phytol (9.67), 2,6,10,14,18,22-tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (all-e) (2.80), heptacosane (3.99), 2,4,4-trimethyl-3-hydroxymethyl-5a-(3-methyl-but-2-enyl)-cyclohexene (10.54), 10,12-tricosadiynoic acid, trimethylsilyl ester (4.12), tetratetracontane (18.73), 3beta.-hydroxyguaia-4(15),10(14),11(13)- trien-6,12-olide 8-(.alpha.,.beta.-dihydroxybutyrate) (11.66), dl-.alpha.-tocopherol (4.42), pentatriacontane (4.45), beta.-sitosterol (7.73). The presence of some of these constituents in the plant extract provides the scientific evidences for the antimicrobial, antitumor, antiviral, antispasmodic, antiperistatic, stomachic and antioxidant properties of the plant.

Keywords: Andrographis paniculata, Phytocompounds, Medicinal plant, GC-MS technique.