WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

INVITRO ANTICANCER ACTIVITY OF CURCUMA LONGA AGAINST HUMAN BREAST CANCER CELL LINE MCF-7

Prasanthi Donipati* and Dr. S. Hara Sreeramulu

ABSTRACT

Turmeric (Curcumo longa) commonly known as Halad in Marathi and Haldi in Hindi is an Indian spice and medicinal plant belonging to Zingiberaceae family and is expensively used in Ayurveda, Unani and Siddha medicine as home remedy for various diseases. Breast cancer is a significant cause of death among women worldwide. The purpose of this study is to test in vitro anticancer activities of the hexane, chloroform and methanolic extracts of Curcuma longa against the human breast cancer cell lines [MCF-7]. The Average values of (Hexane, Chloroform and Methanolic concerntrations) of Curcuma longa were shown in (Table 1), Out of which Chloroform Average values was found to be more 10:62.9, 20:32.1, 40:3.0,80:31.5) than Hexane and Methanolic concerntrations.Agraph was plotted between different concentrations of Curcuma longa (Hexane, Chloroform and Methanolic concerntrations) had different cytotoxicity effects on MCF7 cell line (Figure 1). The plant extract investigated in this study have significant anticancer activity against the breast cancer cell lines tested. Further investigation is required to isolate and elucidate the structure of the compounds responsible for the observed activity.

Keywords: Curcumo longa, breast cancer, anticancer activity, hexane, chloroform and methanolic.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More