Abstract

RATIONAL USE AND PRESCRIBING TRENDS OF ANTIBIOTICS AGAINST STAPHYLOCOCCUS AUREUS POSITIVE INFECTIONS

Vijay Krishna Nidadavolu*, V. Swaroop, Mohd. Amer Ahmed, Dr. Sanjeev S.M, Dr. N.K.Rama and Dr. Syed Imam Rabbani

ABSTRACT

OBJECTIVE: Staphylococcus aureus is the pathogen of great concern, because of its pattern of resistance, primary in hospitals and then spreading to the community. To evaluate the use of antibiotics against Staphylococcus aureus infections in different departments of MVJ hospital. METHOD: A prospective observational study was conducted in different departments of MVJ Medical Hospital. To evaluate the rational use of antibiotics, a total of 100 strains were selected based on the inclusion and exclusion criteria in a period of 6 months. The antibiograms were collected from microbiology department on a daily basis and then the rationality in the selection of antibiotics was determined from the patient records. RESULTS: Out of 100 strains the results have shown that Staphylococcus aureus is the 4th leading cause for infectious diseases. The data indicated that 22% of the samples tested were methicillin resistant Staph aureus. Ampicillin and Linezolid were found to be more resistant and sensitive against Staphylococcus aureus respectively. The appropriateness in selection of antibiotics was found 73% and rational use of antibiotics was found 61%. CONCLUSION: The results suggest that majority of antibiotics in the Staphylococcus aureus infection was prescribed rationally. Linezolid was found to be more sensitive among all the tested antibiotics. The resistance against the antibiotics could be due to the wrong selection of antibiotics, self-medication, missed dose, etc.

Keywords: Staphylococcus aureus, Antibiogram, Rationality in antibiotics.