Abstract

DRUG AND CELL DELIVERY FOR CARDIOVASCULAR REGENERATION SYSTEM

Digambar D. Gaikwad*, Archana D. Chapolikar, Rajendra P. Pawar

ABSTRACT

Cardiovascular diseases (CVD) are fast spreading common diseases found worldwide in all age‘s of peoples. After major myocardial infarction; heart should be effectively repair its weakness or inability. Continuously, an extensive research has in progress for finding the appropriate strategies to induce myocardial regeneration and repairing. A major weakness of known clinical approaches is how to improve patient survival by replacing or regenerating the damaged myocardium after infarction. Number of regenerative strategies has developed in recent years for curing heart disease shifting from conventional approaches. Effective and targeted administration of bioactive agents directly to the diseased tissue is the key in regenerative strategies unlocking, which could improve current conventional treatments. This chapter offers some important findings in these areas and updates the development of new strategies in myocardial regeneration and repairing.

Keywords: Biomaterials, Cell therapy, Heart failure, Medical device, Drug delivery.