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  • WJPPS OCTOBER ISSUE PUBLISHED
  • OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
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Abstract

STUDIES ON ANTIMICROBIAL POTENTIAL OF NEW ISATIN DERIVATIVES

Amit Saxena, Saurabh Sharma, Asif Husain*

ABSTRACT

In a present investigation, a series of new isatin derivatives (3a-i) were prepared by condensing substituted isatins with benzoyl hydrazides. The structures of the synthesized compounds were established on the basis of modern analytical techniques. The title compounds were evaluated for antimicrobial activity against some selected gram (+) gram (-) bacterial strains, and fungal strains. Preliminary screening was carried out for all the compounds and potent compounds were further evaluated for MIC. Anti-tubercular activity was also determined by MABA against Mycobacterium tuberculosis strain H37Rv. The findings are interesting and show that the compounds are biologically active.

Keywords: Oxindole, hydrazide, antibacterial, antifungal, antitubercular activity.


[Full Text Article]

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