Abstract

STUDIES ON ANTIMICROBIAL ACTIVITIES AND PHYTOCHEMICAL ANALYSIS OF LEAF EXTRACTS OF CLERODENDRUM INERME

Priyanka*, Babita Sharma and Neha Mittal

ABSTRACT

In this present work an attempt has been made to assess the in vitro antimicrobial activity of the leaves extracts of Clerodendrum inerme, a common garden hedge against Staphylococcus aureus, Escherichia coli, Lactobacillus acidophilus, Lactobacillus plantarum, Rhizopus oryzae, Aspergillus niger and Mucor spp. Leaves extracts were prepared in different solvents and their antimicrobial screening was carried out by disc diffusion method. The MIC of the extracts was determined. The selected microorganisms were also tested against commercially available antibiotics. Four types of extracts were prepared: aqueous extract, methanolic extract, chloroform extract and ethyl acetate extract. Aqueous extract has not shown any significant zone of inhibition against any test micro-organism. Amongst all the extracts used, Methanolic extract has shown highest effectiveness against all the test micro-organisms

Keywords: Clerodendrum inerme, extracts, antimicrobial screening, phytochemical analysis.