Abstract

INDIAHANDIGODU SYNDROME IN SOUTHERN INDIAHANDIGODU SYNDROME IN SOUTHERN INDIAHANDIGODU SYNDROME IN SOUTHERN INDIAHANDIGODU SYNDROME IN SOUTHERN INDIAHANDIGODU SYNDROME IN SOUTHERN INDIAHANDIGODU SYNDROME IN SOUTHERN INDIAHANDIGODU SYNDROME IN SOUTHERN IND

Ashesh Kumar Gautam*, Sumit Ghimire, Sunil Gyawali and Dilli Ram T

ABSTRACT

Handigodu syndrome is a rare and peculiar osteoarthritic disorder prevalent in Shimoga and chikmaglur in the Karnataka State, southern India. Since it was first noticed in Handigodu village in 1975. About 20% of people from 150 villages are suffering with this disease without any cure. The tragic incidence of 'Handigodu syndrome' has been attributed to be due to the 'long-term' consumption of pesticide-poisoned crabs and fish, As these persons marry only within their communities but no inbreeding was observed in the three families. Clinical presentation is based on the X-ray analysis, Deformity of flixion hip, lumbar lordosis, and pain in hip joints, difficulty in walking, truncal shortening, short stature, dwarfism, and epiphyseal dysplasia at hips, knees, hands and wrists. Lower femoral metaphysis, shortness of femoral necks and broadening, widening of the lower ends of radius and ulna, dysphatic changes shows in hip joints such as flattening of the femoral heads, cox vara and broad short necks. Surgical hip replacement therapy has indicated by the third and fourth decade of life. Life style modifications such as fresh eating habits and avoiding consumption of pesticide-poisoned crabs and fish. Marriages from same communities or from same families should be stopped.

Keywords: Handigodu syndrome, flixion hip, lumbar lordosis.