WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

CAUDAL ANAESTHESIA FOR PAEDIATRIC PATIENTS: COMPARISION BETWEEN LOCAL ANAESTHETIC MIXTURE ALONE AND LOCAL ANAESTHETIC MIXTURE WITH CLONIDINE (1 ?g/Kg)

Aditi A. Dhimar*, Abhisek Raichura and M.R.Upadhyay

ABSTRACT

Background & Objectives: To evaluate the effects of clonidine as an adjuvant to local anesthetic mixture, for caudal anesthesia, in pediatric patients undergoing sub umbilical surgeries. Material & Methods: Fifty ASA –I and II, children from age group of 1 year to 6 years, from either sex, were selected for study. Patients were randomly divided into two groups of 25 each : Clonidine group received : Local anaesthetic mixture + Inj. Adrenaline + Inj. Clonidine (1μg/kg). While in Control group received: Local anaesthetic mixture + Inj. Adrenaline through caudal epidural route. Onset of blockade, hemodynamic and respiratory parameters, sedation and postoperative analgesia were observed. Results: Onset of sensory and motor blockade was significantly earlier in Clonidine group (sensory blockade: 1.32±0.39 minutes, motor blockade : 1.92 ± 0.31minutes), than control group (sensory blockade : 3.02 ± 0.36 minutes, motor blockade : 3.70 ± 0.45 minutes) (‘p’<0.05). Peak effect was achieved significantly earlier in Clonidine group(sensory : 4.76±0.50 minutes, motor : 8.02 ±0.6 minutes ), than control group(sensory : 8.46 ± 0.91minutes, motor: 10.96 ±0.78 minutes). (‘p’<<0.05). Duration of post operative analgesia was significantly longer in Clonidine group (444 ± 54.77 minutes), as compared to Control group (177 ± 36.66 minutes). Conclusion: we conclude, clonidine as an adjuvant o local anesthetic solution, for caudal block significantly shortens time for onset and peak effect for sensory and motor blockade, prolongs duration of analgesia.

Keywords: Caudal anaesthesia, clodine, Lignocaine, Bupivacaine.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More