WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

ACHYRANTHES ASPERA HAVE THE POTENTIAL ANTIOXIDANT PROPERTY IN SCAVENGING FREE RADICALS PRODUCED AS A RESULT OF OXIDATIVE STRESS INDUCED BY ARSENIC.

Shayan Shakeel* Ajay Kumar Sharma* Md Sohail* and Veena Sharma**

ABSTRACT

The current investigation was undertaken to evaluate antioxidant potential role of Achyranthus aspera in arsenic induced oxidative stress in swiss albino mice. In this study, impact of two different plant part (root and leaves) of Achyranthes aspera on adult female mice which were treated with various plant extracts following exposure to arsenic was investigated. 48 Swiss albino mice weighing 20-30g were obtained from Haryana Agricultural University, Hissar, India and were divided into 6 groups each containing 8 mice and received various doses of leaf and root extracts following sodium arsenate treatment. Liver was obtained from the mice and tissue homogenates were used for the estimation of SOD, CAT, GSH, GPx, GST and LPO. Arsenic exposure led to significant rise TBARS (0.313± .002 nmols TBARS/h/g), fall in SOD (0.190± .003 U/mg protein/h), decrease in CAT activity (0.329 ± .001 nmol H2O2 consumed/min/mg protein), rise in GSH (0.072± .005 nmol GSH / g tissue) and significant decrease in GST activity (2.81 ± .14 nmols CDNB conjugates formed/min/mg protein) as compared to control group. From the above findings, it can be concluded that, Achyranthes aspera have the anti-oxidant potential in scavenging free radical produced as a result of oxidative stress induced by arsenic.

Keywords: Achyranthes aspera, anti-oxidant potential.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More