Abstract

IN VITRO INVESTIGATION ON ANTIBACTERIAL ACTIVITY OF SELECTED PROBIOTICS AGAINST SUPERBUG OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) ISOLATED FROM HOSPITAL POPULATIONS

Dr.E.Muralinath and Dr. Lakshmana Swamy Parasa*

ABSTRACT

Aim: This study aims to in vitro investigate the antibacterial activity of selected probiotics against superbug of Methicillin resistant Staphylococcus aureus (MRSA) isolated from Hospital populations by agar well diffusion assay. Objectives: In Vitro Investigation on Antibacterial activity of selected probiotics against superbug of Methicillin resistant Staphylococcus aureus (MRSA) isolated from Hospital populations. Abstract: Antibacterial activity of different parts of selected probiotics like Lactobacillus acidophilus and Lactobacillus casei against methicillin resistant Staphylococcus aureus (MRSA) were determined by agar well diffusion assay. The broth young culture of Lactobacillus acidophilus and Lactobacillus casei revealed highest inhibitory activity against all the tested strains of MRSA with zones of inhibition the range of 20.0 ± 1.0 to 26.0 ± 1.25 mm and 16.0 to 19.15mm respectively. The results of the present study indicate that these probiotics can be used as new leads for the novel plant derived chemotherapeutic agents to confront the problem of nosocomial infections in particular, those involving MRSA.

Keywords: Antibacterial, Methicillin resistant Staphylococcus aureus (MRSA), probiotics agar well diffusion assay.