Abstract

STUDIES ON EFFICACY OF DRUMSTICK LEAVES EXTRACT AND ANTIBIOTICS AGAINST ENTERIC PATHOGENS

Bansode D.S.* and Chavan M.D.

ABSTRACT

In the present work we evaluated the antibacterial activity of crude Drumstick (Moringa oleifera) leaves extract in comparison with Standard antibiotics Cholistin, Erythromycein, Ciprofloxin, Methicillin, Ampicillin and Cephalosporin. For the present study following bacterial cultures were used those were Salmonella typhi (5 strains), E.coli (6 strains), Salmonella paratyphi A (4 strains), Salmonella paratyphi B (5 strains), Shigella flexinary (3 strains) and Shigella dysenteriae (4 strains). Drumstick leaves extract showed highest antibacterial activity against Salmonella typhi strain IV (ZOI- 16mm), E.coli strain I and VI (ZOI- 15mm), Salmonella paratyphi A strain I and IV (ZOI-14mm), Salmonella paratyphi B strain III (ZOI- 18mm), Shigella flexinary strain I (ZOI- 17mm), Shigella dysenteriae strain I (ZOI- 15mm). Salmonella typhi strain V was observed sensitive to antibiotic Ciprofloxin (ZOI- 13mm). Salmonella paratyphi B strain IV showed no ZOI with Drumstick leaves extract but this strain was observed sensitive to antibiotic Ampicillin (ZOI- 15mm). Shigella flexinary strain II was observed sensitive to antibiotic Ampicillin (ZOI- 14mm) and Erythromycein (ZOI- 17mm). Shigella dysenteriae strain III was observed sensitive to antibiotic Cholistin (ZOI- 16mm) and Cephalosporin (ZOI- 15mm). The results of this study showed that some pathogenic enteric bacteria were observed resistant to standard antibiotics but they were observed sensitive to the crude Drumstick leaves extract. The results of the present study also support the medicinal usage of the Drumstick leaves

Keywords: Drumstick (Moringa oleifera), Antimicrobial activity, Enteric pathogens, Standard antibiotics etc.