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Abstract

BENZOTRIAZOLE – THE MOLECULE OF DIVERSE BIOLOGICAL ACTIVITIES

Gitanjali K. Patil*, Harshada C. Patil, Indira M. Patil, Prof. S. L. Borse and
Dr. S. P. Pawar

ABSTRACT

The extensively clinical use of triazole-based medicinal drugs has been promoting increasing effort to develop new structural triazole derivatives. Benzotriazoles as fused aromatic nitrogen heterocycles of benzene ring with triazole exhibit wide potentialities in medicinal chemistry since some anticancer benzotriazole compounds like vorozole and 4,5,6,7-tetrabromo-1H-benzotriazole (TBB) were used in clinical therapy. Outstanding developments of benzotriazole compounds in medicinal chemistry, including as anticancer, antifungal, antibacterial, antitubercular, antiviral, antioxidative, antiparasitic, antioxidative agents and so on. Hopefully, this contribution will be helpful to develop benzotriazole-based drugs with high bioactivity and low toxicity.

Keywords: Benzotriazole; Anticancer; Antifungal; Antibacterial; Antitubercular; Antiviral; Antiparasitic; Antioxidative.


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