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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

IN VITRO CYTOTOXICITY, PHYTOCHEMISTRY AND GC-MS ANALYSIS OF PITHECELLOBIUM DULCE LEAVES.

Poongodi. T* and Hemalatha. R

ABSTRACT

The objective of the study was to investigate the preliminary phytochemical screening, GC-MS and In vitro cytotoxicity assay of leaf extract of Pithecellobium dulce. Phytochemical screening revealed the presence of active plant metabolites like alkaloids, flavonoids, glycosides, phenol, tannins, diterpenes, saponins and phytosterols. It was further continued to identify 18 different compounds of medicinal use in the Pithecellobium dulce by GC-MS analysis. The study also investigated about the Invitro cytotoxic nature of Pithecellobium dulce leaves in breast cancer cell line (MCF-7) using MTT assay. IC50 value was found to be 112μg/ml. 100% cell inhibition occurred at 300 μg/ml.

Keywords: Pithecellobium dulce, MCF-7 cell line, GC-MS analysis, Cytotoxicity, MTT assay.

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