Abstract

AN OVERVIEW ON BILAYERED TABLET TECHNOLOGY

Chintan R Dhorajia*, Jaymin M Patel, Kaushika S Patel, Shreeraj Shah and Pratik upadhyay

ABSTRACT

Over the past 30 years stated that the expense and complications involved in market ing newdrug entities have increased, with concomitant recognition of therapeutic advantages of controlled drug delivery, greater attention has been focused on development of sustained or controlled release drug delivery systems. Bilayer tablet is new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system. Controlled release dosage forms have been extensively used to improve therapy with several important drugs. Bilayer tablet is suitable for sequential release of two drugs in combination, separate two incompatible substances and also for sustained release tablet in which one Layer is immediate release as initial dose and second layer is maintenance dose. Bilayer tablet is improved beneficial technology to overcome the shortcoming of the single layered tablet.

Keywords: Bilayer tablet, Bilayer tablet press, GMP requirements, OROS push pull technology, DUROS technology.